PLURONIC相关论文
水凝胶具有三维网络结构,近年来广泛应用于药物控释领域。黏膜粘附给药系统（mucoadhesive drug delivery system,MDDS）是以具有生物......
To design a new type of antitumor nanodrug carrier with good biocompatibility,a drug delivery system with a 2.19％ drug-lo......
在食物消化过程中，淀粉将会与不同亲疏水性物质混合。直链淀粉中疏水性部位与不同亲疏水性物质相互作用，对淀粉酶水解淀粉的影响尚不......
Preparation of Novel Liquid Suppository Through In Situ Gelling for Site-Targeting Delivery of Anti-
Conventional suppositories are solid forms which often cause discomfort during insertion.The leakage of suppositories fr......
Effect of additives on the cloud point aggregation of an ethylene oxide-propylene oxide triblock cop
The effect of copolymer concentration and additives on the cloud point temperature of hydrophobic PEO-PPO-PEO block copo......
为提高阳离子脂质体介导的细胞摄取反义寡核苷酸(antisenseoligodeoxynucleotides,ODN)的效率,我们在以3β[N-(N,N-二甲基氨基乙基......
Methotrexate-Conjugated Polymeric Micelles in the Folate Receptor-Rich Cancer Treatment and Safety E
Due to its high structural similarity to folic acid (FA) and the high expression of folate receptor in most solid tumors......
Highly Effective Chemoimmunotherapy Mediated by Erythrocyte Membrane Camouflaged Thermoresponsive Na
Chemotherapy is still the treatment modality of choice for most advanced cancers.However,for solid tumors in particular,......
In vitro targeting behaviors of Folate-conjugate Pluronic F127/poly (lactic-co-glycolic) nanoparticl
Novel Pluronic F127/poly (lactic-co-glycolic) block copolymer PLGA-F127-PLGA and Folated FA-F127-PLGA were synthesized a......
Nowadays, lots of investigators draw attention to multidrug resistance(MDR) in cancer.The MDR is mostly due to the overe......
Pluronic-attached polyamidoamine dendrimer conjugates for targeted delivery of doxorubicin and rever
Multidrug resistance (MDR) is one of the major reasons for the failure of chemotherapy.In this study, a series of pluron......
Characterization and modulation of drug resistance of chemical conjugation of Methotrexate in Pluron
Multidrug resistance (MDR) in cancer is a major cause for the failure of anti-cancer chemotherapy with elevated expressi......
Docetaxel loaded Pluronic P105/F127 mixed micelles against Drug-Resistant Lung Adenocarcinoma Cell L
The aim of this study was to investigate the antitumor effect of docetaxel (DTX) loaded Pluronic P105/F127 mixed micelle......
BaCO < 潜水艇 class= “ a-plus-plus ” > 3 </sub>/C composites 被作为碳来源，用酉分的 resol 与碳化进程相结合的一个多部件合......
二例产后大出血导致严重贫血的病人,因宗教原因拒绝输血,使用20%Fluosol-DA 抢救获得成功。20%Fluosol-DA 的配方为:全氟化+氢萘(......
Near infrared(NIR) light induced photothermal effect for Fe_3O_4 nanoparticles,contained in Pluronic F127 micelles,has b......
Facile Synthesis of Gold-nanoparticles-decorated Polymer Assemblies and Core-Shell Gold Nanoparticle
Synthesis of gold nanoparticles(AuNPs) and Pluronic triblock copolymer composite in aqueous medium was studied.Gold-poly......
Thermo-responsive polyrotaxane (PR)-based triblock copolymers were synthesized via the atom transfer radical polymerizat......
Poly(vinylidene fluoride)(PVDF) has become one of the most popular materials for membrane prepara-tion via nonsolvent in......
目的:制备载多烯紫杉醇(DTX)的Solutol HS15/Pluronic F127混合胶束系统(SF-DTX),并对处方进行优化,对最佳处方的形态、粒径、包封......
PLURONIC共聚物是由环氧乙烷(EO)和环氧丙烷(PO)共聚而成的一类二元醇,其通式是HO(C_2H_4O)_a(C_3H_6O)_b(C_2H_4O)_cH,其中b≥15......
本文测定了三种 Pluronic 共聚物(L61、L64和 F68)和聚丙二醇(分子量为2025)的存在对于石英/水/空气和石英/水/环己烷的接触角的影......
FUNCTIONSOF CELL SSCAFFOLD IN THE TISSUE ENGINEERING Cell,cells scaffold and the construction of tissue and organ ar......
东日本学园大学的宫崎正三博士和城西大学的森本雍宪博士访华期间,应中国药学会上海分会的邀请,于1985年6月1日在沪作了学术报告......
水难溶性抗癌药物的非胃肠道给药所面临的主要问题是这些药物与水、盐溶液或血液混合即析出沉淀。使药物不为生物所利用,同时还可......
阴离子清洁剂十二烷基硫酸钠(SLS)通常用作刺激斑贴实验。本研究用羟丙甲基纤维素(Methocel E_4M凝胶)、聚氧乙烯、聚氧丙烯聚合......
以自由基溶液聚合方法制备了聚(甲基丙烯酸-co-泊洛沙姆)共聚物水凝胶,研究凝胶的平衡溶胀性质及模型药物(VB12)在溶胀和收缩状态......
目的:表面活性剂在固体脂质纳米粒的制备过程中扮演着重要角色,为规避药物对体系的影响,本文选用4种表面活性剂制备了空白而具有良......
Aim:To investigate the preparation,in vitro release,in vivo pharmacokineticsand tissue distribution of a novel polymeri......
A new dynamic density functional method(Mesodynamics) has been used to simulate microphase separation kinetics of the aq......
目的研究普流罗尼克(Pluronic F127,F68,P85,P123)对小肠P-糖蛋白(P-gp)的调控作用。方法采用MTT法检测不同质量浓度的Pluronic对C......
目的制备载有喜树碱的混合胶束系统,增加喜树碱的载药量。方法以Pluronic P105(P105)和Pluronic L61(L61)为材料,难溶性抗癌药物喜......
Well-organized mesoporous titania particles and thin films were successfully synthesized by using tetrabutyl titanate as......
Micellization,Interaction and Microenvironment in the Mixed Solution of Pluronics and Surfynol 104 w
The micellization,intermolecular interaction and microenvironment of molecular segments in the mixed aqueous solution of......
This study examined the effect of P85(a pluronic block copolymer)and microbubble(MB)ultrasound contrast agents under ult......
对胶束尺寸和性质的有效调控是具有重要意义的研究课题。研究发现，压缩CO2可有效溶胀Pluronic胶束；以CO2-溶胀的Pluronic胶束为......
本文采用三种常见的阴离子表面活性剂与非离子表面活性剂Pluronic P123进行复配，并将之用作合成高度有序介孔材料的结构导向剂，探讨......
采用生物相容性聚合物胶束材料聚乙二醇-聚乳酸(mPEG-PLA和普朗尼克P105 (P105),构建了全新的混合胶束体系,用于提高难溶性麻醉药......
设计以温敏凝胶作为颗粒酶B质粒 (pGZMB) 和盐酸多柔比星 (DOX·HCl) 的共载载体以期实现基因和化疗药物联合治疗.选择支链型聚乙......
以聚乙二醇99-b-聚丙二醇69-b-聚乙二醇99(PEO99-b-PPO69-b-PEO99 Pluronic F127)为大分子引发剂,引发己内酯(CL)和6-乙酸苄酯-己......
本课题组在前期已经研究了pluronic P-105[1]-尿激酶缓释系统在低频超声的控制下缓慢释放,在大鼠脑出血中,其溶解血肿的效果要优于......
Facile Synthesis of Gold-nanoparticles-decorated Polymer Assemblies and Core-Shell Gold Nanoparticle
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
背景：超顺磁四氧化三铁纳米粒子(Fe 3 O 4 NPs)被广泛应用于MRI成像，为防止其聚集和实现高精度肿瘤诊断，制备高度稳定性、生物相容性......
以Pluronic P123与F127(质量比2∶1)为载体,采用薄膜水化法制备包载抗癫痫药拉莫三嗪(lamotrigine,1)的混合胶束(PF胶束)并表征。......
