本文应用放射性示踪技术对大鼠口服3H-RNA药代动力学参数和吸收规律进行了分析,现报道如下。受试大鼠(Wister鼠,体重200~250g,雌雄各半)随机分4组,每组6只,动物给药之前禁食12h,口服为3组,即40mg/kg、80mg/kg和160mg/kg;静注为1组,即80mg/kg。给药后不同时间,经眼耻静脉采血,每 In this paper, radioactive tracer technology to rat oral 3H-RNA pharmacokinetic parameters and absorption were analyzed, are reported below. The rats (Wister rats weighing 200-250 g, half male and half female) were randomly divided into 4 groups with 6 rats in each group. Animals were fasted for 12 hours before oral administration, and were orally administered in groups of 40, 40 mg / kg, 80 mg / kg and 160 mg / kg; intravenous group 1, that is 80mg / kg. At different times after administration, the blood was collected by the ocular and intravenous shame